The solution lies in The very fact there are many isoforms of every troponin subunit that are encoded by distinctive genes, a number of that happen to be expressed selectively in cardiac muscle mass. Even though TnI and TnT have unique cardiac and skeletal isoforms, they share a standard isoform of TnC: the slow-twitch skeletal muscle mass isoform
Elucidation on the physiologically distinctive subunits of troponin in 1973 tremendously facilitated our knowledge of cardiac contraction. Although troponins are expressed in both skeletal and cardiac muscle mass, you will find isoforms of troponin I/T expressed selectively in the center. By exploiting cardiac-limited epitopes in these proteins, Th
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